#夜·读 # An individual human being becomes who he or she is only because of what he or she perceives. You are who you are right now only because of what you have perceived in your life until now, and you will be who you will be only because of what you will perceive in future. There are only two dimensions of experience – inner experiences and outer experiences.Enhancing perception．

【Nature | 线粒体上的清道夫蛋白——Ubx2】大多数线粒体的结构和功能蛋白都是由核基因编码，并由细胞质内的核糖体翻译合成前体，前体蛋白经过复合体 (translocase of the outer mitochondrial membrane) 形成的通道进入线粒体内部。然而，从TOM 通道中去除未成功导入的前体蛋白，实现结构性质控的机制目前尚未有报道。
近日，来自德国弗莱堡大学的Thomas Becker团队在Nature上发表文章，发现在啤酒酵母中Ubx2不仅参与内质网相关的蛋白降解，而且与线粒体膜上TOM复合体结合并招募AAA ATPase Cdc48去除TOM通道中未成功导入的前体蛋白。后者在非应激状态下持续性地监管TOM通道以防前体蛋白堵塞，保证线粒体的蛋白导入能力，抑制线粒体蛋白诱导的应激反应。该研究揭示了Ubx2招募Cdc48，降解TOM通道中未成功导入的前体蛋白，维持TOM通畅。填补了线粒体蛋白质控机制方面的空白，具有重大的意义。https://t.cn/Aip1GOEV

#返场预告新专辑# 美国南部说唱大牌Big K.R.I.T.在今天公开即将于下月12号发布的全新专辑 K.R.I.T. IZ HERE的曲目表！J. Cole, Rico Love, Lil Wayne, Saweetie, Yella Beezy等人参与客串！

01 K.R.I.T. HERE
02 High End Country (Interlude)
03 I Been Waitin
04 I Make It Easy
05 Addiction [ft. Lil Wayne and Saweetie]
06 Energy
07 Obvious [ft. Rico Love]
08 I Made [ft. Yella Beezy]
09 Everytime [ft. Baby Rose]
10 Believe
11 Prove It [ft. J. Cole]
12 Family Matters
13 “Blue Flame” (Interlude)
14 Blue Flame Ballet
15 Learned From Texas
16 Outer Space
17 High Beams [ft. WOLFE de MÇHLS]
18 Life in the Sun [ft. Camper]
19 M.I.S.S.I.S.S.I.P.P.I.