今天的文献分享是关于长期臭氧暴露的危害。多项关于长期暴露于环境臭氧的研究发现，环境臭氧浓度的增加与肺功能下降有关。比较令人担忧的是“几项针对年轻人的研究表明，终生累积的臭氧暴露与肺功能参数下降（与小气道阻塞一致）之间存在关联”（P1）。
环境中的臭氧浓度已经很低了，但长期暴露依然会对肺功能产生影响。因此我的个人意见是，生活中尽量还是避免常规使用会产生臭氧的消毒方式，能少积累点臭氧暴露就少积累一点吧。非要用的时候，尽量选择能够即刻彻底通风的环境，不要在存在可能的通风死角的室内用。
Balmes JR. Long-Term Exposure to Ozone and Small Airways: A Large Impact? Am J Respir Crit Care Med. 2022 Feb 15;205(4):384-385. doi: 10.1164/rccm.202112-2733ED. PMID: 35007495; PMCID: PMC8886953.
Niu Y, Yang T, Gu X, Chen R, Meng X, Xu J, Yang L, Zhao J, Zhang X, Bai C, Kang J, Ran P, Shen H, Wen F, Huang K, Chen Y, Sun T, Shan G, Lin Y, Wu S, Zhu J, Wang R, Shi Z, Xu Y, Ye X, Song Y, Wang Q, Zhou Y, Ding L, Yang T, Yao W, Guo Y, Xiao F, Lu Y, Peng X, Zhang B, Xiao D, Wang Z, Zhang H, Bu X, Zhang X, An L, Zhang S, Cao Z, Zhan Q, Yang Y, Liang L, Cao B, Dai H, Wu T, He J, Li H, Kan H, Wang C; China Pulmonary Health Study Group. Long-Term Ozone Exposure and Small Airway Dysfunction: The China Pulmonary Health (CPH) Study. Am J Respir Crit Care Med. 2022 Feb 15;205(4):450-458. doi: 10.1164/rccm.202107-1599OC. PMID: 34813411.
Zhao T, Markevych I, Fuertes E, de Hoogh K, Accordini S, Boudier A, Casas L, Forsberg B, Garcia Aymerich J, Gnesi M, Holm M, Janson C, Jarvis D, Johannessen A, Jörres RA, Karrasch S, Leynaert B, Maldonado Perez JA, Malinovschi A, Martínez-Moratalla J, Modig L, Nowak D, Potts J, Probst-Hensch N, Sánchez-Ramos JL, Siroux V, Urrutia Landa I, Vienneau D, Villani S, Jacquemin B, Heinrich J. Impact of long-term exposure to ambient ozone on lung function over a course of 20 years (The ECRHS study): a prospective cohort study in adults. Lancet Reg Health Eur. 2023 Sep 1;34:100729. doi: 10.1016/j.lanepe.2023.100729. PMID: 37691742; PMCID: PMC10482740.
环境中的臭氧浓度已经很低了，但长期暴露依然会对肺功能产生影响。因此我的个人意见是，生活中尽量还是避免常规使用会产生臭氧的消毒方式，能少积累点臭氧暴露就少积累一点吧。非要用的时候，尽量选择能够即刻彻底通风的环境，不要在存在可能的通风死角的室内用。
Balmes JR. Long-Term Exposure to Ozone and Small Airways: A Large Impact? Am J Respir Crit Care Med. 2022 Feb 15;205(4):384-385. doi: 10.1164/rccm.202112-2733ED. PMID: 35007495; PMCID: PMC8886953.
Niu Y, Yang T, Gu X, Chen R, Meng X, Xu J, Yang L, Zhao J, Zhang X, Bai C, Kang J, Ran P, Shen H, Wen F, Huang K, Chen Y, Sun T, Shan G, Lin Y, Wu S, Zhu J, Wang R, Shi Z, Xu Y, Ye X, Song Y, Wang Q, Zhou Y, Ding L, Yang T, Yao W, Guo Y, Xiao F, Lu Y, Peng X, Zhang B, Xiao D, Wang Z, Zhang H, Bu X, Zhang X, An L, Zhang S, Cao Z, Zhan Q, Yang Y, Liang L, Cao B, Dai H, Wu T, He J, Li H, Kan H, Wang C; China Pulmonary Health Study Group. Long-Term Ozone Exposure and Small Airway Dysfunction: The China Pulmonary Health (CPH) Study. Am J Respir Crit Care Med. 2022 Feb 15;205(4):450-458. doi: 10.1164/rccm.202107-1599OC. PMID: 34813411.
Zhao T, Markevych I, Fuertes E, de Hoogh K, Accordini S, Boudier A, Casas L, Forsberg B, Garcia Aymerich J, Gnesi M, Holm M, Janson C, Jarvis D, Johannessen A, Jörres RA, Karrasch S, Leynaert B, Maldonado Perez JA, Malinovschi A, Martínez-Moratalla J, Modig L, Nowak D, Potts J, Probst-Hensch N, Sánchez-Ramos JL, Siroux V, Urrutia Landa I, Vienneau D, Villani S, Jacquemin B, Heinrich J. Impact of long-term exposure to ambient ozone on lung function over a course of 20 years (The ECRHS study): a prospective cohort study in adults. Lancet Reg Health Eur. 2023 Sep 1;34:100729. doi: 10.1016/j.lanepe.2023.100729. PMID: 37691742; PMCID: PMC10482740.
#成毅莲花楼# cy#lanvin全球代言人成毅#
───❥ cheng yi ───♥︎
喜欢大概是 望你 却不愿声张
喜欢大概是 遇你 却不敢驻足
I was fine when you were on the stage and I was in the crowd.❄️❄️❄️✨✨✨
───❥ fu shi qi ───♥︎
成毅｜狐妖小红娘王权篇｜王权富贵｜莲花楼｜李莲花｜李相夷
───❥ cheng yi ───♥︎
喜欢大概是 望你 却不愿声张
喜欢大概是 遇你 却不敢驻足
I was fine when you were on the stage and I was in the crowd.❄️❄️❄️✨✨✨
───❥ fu shi qi ───♥︎
成毅｜狐妖小红娘王权篇｜王权富贵｜莲花楼｜李莲花｜李相夷
#BBBuild[超话]#Wo yuan bian cheng tong hua li ni ai de na ge tian shi, zhang kai Shuang shou bian cheng chi bang shou hu ni.
I am willing to become the angel you love in fairy tales, spreading my hands and turning into wings to protect you.
我愿变成童话里你爱的那个天使，张开双手变成翅膀守护你。
I am willing to become the angel you love in fairy tales, spreading my hands and turning into wings to protect you.
我愿变成童话里你爱的那个天使，张开双手变成翅膀守护你。
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